Central pontine myelinolysis following correction of hyponatremia: MRI diagnosis
Autor: | Lorenzo Morlan, Javier Mosquera González, H. Liaño, Elena Rodríguez, Pedro Escartin, Carlos Jimenez-Ortiz |
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Rok vydání: | 1990 |
Předmět: |
Adult
medicine.medical_specialty Pathology Lesion Pons medicine Humans medicine.diagnostic_test business.industry Pons Varolii nutritional and metabolic diseases Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Neurology Mri diagnosis Central pontine myelinolysis Female Neurology (clinical) Radiology medicine.symptom Hyponatremia business Complication Demyelinating Diseases |
Zdroj: | European neurology. 30(3) |
ISSN: | 0014-3022 |
Popis: | A 37-year-old woman with hepatic failure developed a locked-in syndrome after correction of a severe symptomatic hyponatremia. Magnetic resonance imaging showed a lesion involving the basis pontis and extending into the midbrain, consistent with central pontine myelinolysis. In this patient the rate of correction of hyponatremia was within the range considered sure by several authors, but factors such as hepatic encephalopathy, a single generalized seizure and correction of hyponatremia in 42 h with a change in serum sodium concentration of 34 mmol/l were present, and they could have been etiologically relevant. This case, like other recent reports, suggests new views about the pathogenesis of cerebral demyelinating lesions in patients with hyponatremia. |
Databáze: | OpenAIRE |
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