Do postliver transplant patients need thromboprophylactic anticoagulation?
| Autor: | Andreas Karachristos, Amar Nath Mukerji, Ashokkumar Jain, Manoj Maloo, David R. Johnson |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Standard of care business.industry Deep vein Anticoagulants Hematology General Medicine Budd-Chiari Syndrome medicine.disease Thrombosis Portal vein thrombosis Surgery Pulmonary embolism Liver Transplantation Hepatic artery thrombosis medicine.anatomical_structure Postoperative Complications Budd–Chiari syndrome Medicine Humans Transplant patient International Normalized Ratio business Pulmonary Embolism |
| Zdroj: | Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 20(7) |
| ISSN: | 1938-2723 |
| Popis: | Postoperative thromboprophylactic anticoagulation against Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) is standard of care with current evidence-based guidelines. However, majority of liver transplant (LT) patients have thrombocytopenia and/or prolonged INR before surgery. Studies or guidelines regarding role of prophylactic anticoagulation after LT are lacking. There is a need to balance the risk of thrombosis with significant hemorrhage, implying those needing transfusion or return to OR due to bleeding. We conclude that after LT, anticoagulation is not required routinely for DVT/PE prophylaxis. Rather, it is indicated in specific circumstances, chiefly for prophylaxis of hepatic artery thrombosis or portal vein thrombosis in cases with use of grafts, pediatric cases, small size vessels, Budd Chiari syndrome, amongst others. |
| Databáze: | OpenAIRE |
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