Dental Afferents Project onto Gustatory Neurons in the Nucleus of the Solitary Tract
| Autor: | Aurelie Vandenbeuch, Fawzia Zerari-Mailly, Adeline Braud, Yves Boucher |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Sensory Receptor Cells
Mandibular Nerve Stimulation Biology Inferior alveolar nerve Rats Sprague-Dawley Immunolabeling Tongue Neck Muscles Neural Pathways Solitary Nucleus medicine Animals Neurons Afferent Evoked Potentials General Dentistry Fluorescent Dyes Parabrachial Nucleus Reticular Formation Solitary tract Dendrites Anatomy Immunohistochemistry Electric Stimulation Rats Electrophysiology medicine.anatomical_structure nervous system Taste Chorda Tympani Nerve Brainstem Single-Cell Analysis Proto-Oncogene Proteins c-fos Nucleus Brain Stem |
| Zdroj: | Journal of Dental Research. 91:215-220 |
| ISSN: | 1544-0591 0022-0345 |
| Popis: | The aim of this study was to investigate the inferior alveolar nerve (IAN) and chorda tympani (CT) projections onto gustatory neurons of the nucleus of the solitary tract (NST) in the rat by immunochemical and electrophysiological techniques. IAN afferents were retrogradely labeled. NST neurons were labeled either by retrograde tracer injection into the parabrachial nucleus (PBN) or by c-Fos mapping after CT activation. NST neurons responding to tastant stimulation were recorded in vivo before and after electrical stimulation of the IAN. Results from the immunolabeling approach showed IAN boutons “en passant” apposed to retrogradely labeled neurons from PBN and to CT-activated neurons in the NST. Recordings of single NST neurons showed that the electrical stimulation of the IAN significantly decreased CT gustatory responses. Analysis of these data provides an anatomical and physiological basis to support trigeminal dental and gustatory interactions within the brainstem. |
| Databáze: | OpenAIRE |
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