Quantitative evaluation of gap junctions in rat brown adipose tissue after cold acclimation
| Autor: | G Schneider-Picard, J L Carpentier, L Girardier |
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| Rok vydání: | 1984 |
| Předmět: |
Male
Cell signaling Physiology Period (gene) Acclimatization Biophysics Gap junction Adipose tissue Rats Inbred Strains Cell Biology Anatomy Biology Rats Cold Temperature medicine.anatomical_structure Intercellular Junctions Adipose Tissue Brown Brown adipose tissue Cold acclimation medicine Animals Intracellular |
| Zdroj: | The Journal of membrane biology. 78(2) |
| ISSN: | 0022-2631 |
| Popis: | The decrease in the metabolic capacity of rat brown adipose tissue during the late postnatal period can be reversed by cold acclimation of the animals. In order to find out whether a parallel decrease in capability for intercellular communication observed during this period is also reversed by cold acclimation, gap junction size and number per unit area of cell surface have been quantified in freeze-fracture replicas; cell diameters have been measured in semi-thin sections. It was found that the specific number of gap junctions remains unchanged during cold acclimation. However, the mean gap junction size increases by 75% and the ratio of gap junctional area per cell volume, an index for intercellular exchange capacity, is doubled. This result illustrates further the parallelism between metabolic capacity and cell communication in brown fat. |
| Databáze: | OpenAIRE |
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