Choice of anesthetic agents for peribulbar anesthesia

Autor: Raymond H. Hollands, Philip H. House, Michael Schulzer
Rok vydání: 1991
Předmět:
Zdroj: Journal of Cataract and Refractive Surgery. 17:80-83
ISSN: 0886-3350
DOI: 10.1016/s0886-3350(13)80989-3
Popis: To determine the effectiveness of various combinations of lidocaine, epinephrine, and hyaluronidase with bupivacaine, a prospective, randomized, masked study on 117 patients having cataract extraction under local anesthesia was undertaken. All patients were given a 9 ml peribulbar block by one surgeon, and a graded assessment of analgesia and akinesia was made in a masked fashion one hour later. A mixture using all these agents gave significantly better results than any of the combinations ( P =.001). No single agent was shown to be the major determinant of effectiveness. The result suggests a synergistic effect found only when all the agents are combined.
Databáze: OpenAIRE