Choice of anesthetic agents for peribulbar anesthesia
Autor: | Raymond H. Hollands, Philip H. House, Michael Schulzer |
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Rok vydání: | 1991 |
Předmět: |
Peribulbar anesthesia
medicine.medical_specialty Lidocaine medicine.drug_class Cataract Extraction Double-Blind Method Hyaluronidase medicine Humans Local anesthesia Prospective Studies Anesthetics Local Pain Measurement Bupivacaine Local anesthetic business.industry Drug Synergism Sensory Systems Surgery Ophthalmology Epinephrine Anesthesia Anesthetic business Conjunctiva Anesthesia Local medicine.drug |
Zdroj: | Journal of Cataract and Refractive Surgery. 17:80-83 |
ISSN: | 0886-3350 |
DOI: | 10.1016/s0886-3350(13)80989-3 |
Popis: | To determine the effectiveness of various combinations of lidocaine, epinephrine, and hyaluronidase with bupivacaine, a prospective, randomized, masked study on 117 patients having cataract extraction under local anesthesia was undertaken. All patients were given a 9 ml peribulbar block by one surgeon, and a graded assessment of analgesia and akinesia was made in a masked fashion one hour later. A mixture using all these agents gave significantly better results than any of the combinations ( P =.001). No single agent was shown to be the major determinant of effectiveness. The result suggests a synergistic effect found only when all the agents are combined. |
Databáze: | OpenAIRE |
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