Sustained Ventricular Tachycardia and Its Successful Prophylaxis During High-Dose Bolus Interleukin-2 Therapy for Metastatic Renal Cell Carcinoma
| Autor: | Gail Cynthia Leichman, Leslie Oleksowicz, Paul Escott, Edward Spangenthal |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
Tachycardia Cancer Research medicine.medical_treatment Antineoplastic Agents Antiarrhythmic agent Ventricular tachycardia Bolus (medicine) Renal cell carcinoma Humans Medicine cardiovascular diseases Carcinoma Renal Cell business.industry Sotalol Middle Aged medicine.disease Kidney Neoplasms Discontinuation Oncology Anesthesia Tachycardia Ventricular cardiovascular system Interleukin-2 medicine.symptom business Anti-Arrhythmia Agents medicine.drug Kidney disease |
| Zdroj: | American Journal of Clinical Oncology: Cancer Clinical Trials. 23:34-36 |
| ISSN: | 0277-3732 |
| DOI: | 10.1097/00000421-200002000-00009 |
| Popis: | In the setting of interleukin-2 (IL-2) administration, tachycardias of ventricular origin are classified as serious, grade IV toxicities, necessitating the discontinuation of therapy. In this report, we describe a patient with renal cell carcinoma who experienced ventricular tachycardia while undergoing treatment with high-dose bolus IL-2. Prophylaxis with sotalol permitted the successful completion of his first cycle of treatment, without any recurrent rhythm disturbances. |
| Databáze: | OpenAIRE |
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