Cylindrical ultrasonic transducers for cardiac catheter ablation
| Autor: | J. Dennie, Ding Sheng He, Kullervo Hynynen, J.E. Zimmer, Frank I. Marcus, W.N. Simmons, Maria L. Aguirre |
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| Rok vydání: | 1997 |
| Předmět: |
Materials science
business.industry Ultrasonic Therapy medicine.medical_treatment Transducers Ultrasound Biomedical Engineering Catheter ablation Equipment Design In Vitro Techniques Lesion depth Ablation In vivo tests Dogs Transducer Evaluation Studies as Topic Catheter Ablation medicine Animals Feasibility Studies Tissue necrosis Ultrasonic sensor Cardiac Surgical Procedures business Biomedical engineering |
| Zdroj: | IEEE Transactions on Biomedical Engineering. 44:144-151 |
| ISSN: | 0018-9294 |
| DOI: | 10.1109/10.552244 |
| Popis: | This study was designed to evaluate the feasibility of using cylindrical ultrasound transducers mounted on a catheter for the ablation of cardiac tissues. In addition, the effects of ultrasound frequency and power was evaluated both using computer simulations and in vitro experiments. Frequencies of 4.5, 6, and 10 MHz were selected based on the simulation studies and manufacturing feasibility. These transducers were mounted on the tip of 7-French catheters and applied in vitro to fresh ventricular canine endocardium, submerged in flowing degassed saline at 37/spl deg/C. When the power was regulated to maintain transducer interface temperature at 90-100/spl deg/C, the 10-, 6-, and 4.5-MHz transducers generated a lesion depth of 5.9/spl plusmn/0.2 mm, 4.6/spl plusmn/1.0 mm, and 5.3/spl plusmn/0.9 mm, respectively. The 10-MHz transducer was chosen for the in vivo tests since the maximum lesion depth was achieved with the lowest power. Two dogs were anesthetized and sonications were performed in both the left and right ventricles. The 10-MHz cylindrical transducers caused an average lesion depth of 6.4/spl plusmn/2.5 mm. In conclusion, the results show that cylindrical ultrasound transducers can be used for cardiac tissue ablation and that they may be able to produce deeper tissue necrosis than other methods currently in use. |
| Databáze: | OpenAIRE |
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