Thyroid function analysis in COVID-19: A retrospective study from a single center
Autor: | Uzma Ishaq, Asmara Malik, Muhammad Shoaib, Jahanzeb Malik, Muhammad Javaid, Tayyaba Zahid |
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Rok vydání: | 2021 |
Předmět: |
Male
Viral Diseases Pulmonology Peptide Hormones Thyroid Gland Pilot Projects Artificial Gene Amplification and Extension Disease 030204 cardiovascular system & hematology Logistic regression Single Center Biochemistry Polymerase Chain Reaction Gastroenterology Procalcitonin Medical Conditions 0302 clinical medicine Epidemiology Medicine and Health Sciences Medicine Virus Testing Thyroid Multidisciplinary Chemical Reactions Middle Aged Chemistry Infectious Diseases medicine.anatomical_structure Physical Sciences Female Anatomy Thyroid function Research Article Thyroid Hormones medicine.medical_specialty Science Endocrine System 030209 endocrinology & metabolism Research and Analysis Methods Reactants 03 medical and health sciences Diagnostic Medicine Internal medicine Humans Thyroid-Stimulating Hormone Molecular Biology Techniques Pandemics Molecular Biology Retrospective Studies business.industry COVID-19 Biology and Life Sciences Covid 19 Retrospective cohort study Pneumonia medicine.disease Hormones business Hormone |
Zdroj: | PLoS ONE PLoS ONE, Vol 16, Iss 3, p e0249421 (2021) |
ISSN: | 1932-6203 |
Popis: | Background and objective Coronavirus disease 2019 (COVID-19) is an on-going epidemic with a multitude of long-ranging effects on the physiological balance of the human body. It can cause several effects on thyroid functions as well. We aimed to assess the lasting sequelae of COVID-19 on thyroid hormone and the clinical course of the disease as a result. Methods Out of 76 patients, 48 patients of COVID-19 positive and 28 patients of COVID-19 negative polymerase chain reaction (PCR) were assessed for thyroid functions, IL-6, and Procalcitonin between moderate, severe, and critical pneumonia on HRCT. Results Seventy-five percent of patients with COVID-19 had thyroid abnormalities and higher IL-6 levels (76.10 ± 82.35 vs. 6.99 ± 3.99, 95% CI 52.18–100.01, P-value Conclusion This pilot study from Pakistan demonstrates that changes in serum TSH and TT3 levels may be important manifestations of the courses of COVID-19 pneumonia. |
Databáze: | OpenAIRE |
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