Thyroid function analysis in COVID-19: A retrospective study from a single center

Autor: Uzma Ishaq, Asmara Malik, Muhammad Shoaib, Jahanzeb Malik, Muhammad Javaid, Tayyaba Zahid
Rok vydání: 2021
Předmět:
Male
Viral Diseases
Pulmonology
Peptide Hormones
Thyroid Gland
Pilot Projects
Artificial Gene Amplification and Extension
Disease
030204 cardiovascular system & hematology
Logistic regression
Single Center
Biochemistry
Polymerase Chain Reaction
Gastroenterology
Procalcitonin
Medical Conditions
0302 clinical medicine
Epidemiology
Medicine and Health Sciences
Medicine
Virus Testing
Thyroid
Multidisciplinary
Chemical Reactions
Middle Aged
Chemistry
Infectious Diseases
medicine.anatomical_structure
Physical Sciences
Female
Anatomy
Thyroid function
Research Article
Thyroid Hormones
medicine.medical_specialty
Science
Endocrine System
030209 endocrinology & metabolism
Research and Analysis Methods
Reactants
03 medical and health sciences
Diagnostic Medicine
Internal medicine
Humans
Thyroid-Stimulating Hormone
Molecular Biology Techniques
Pandemics
Molecular Biology
Retrospective Studies
business.industry
COVID-19
Biology and Life Sciences
Covid 19
Retrospective cohort study
Pneumonia
medicine.disease
Hormones
business
Hormone
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0249421 (2021)
ISSN: 1932-6203
Popis: Background and objective Coronavirus disease 2019 (COVID-19) is an on-going epidemic with a multitude of long-ranging effects on the physiological balance of the human body. It can cause several effects on thyroid functions as well. We aimed to assess the lasting sequelae of COVID-19 on thyroid hormone and the clinical course of the disease as a result. Methods Out of 76 patients, 48 patients of COVID-19 positive and 28 patients of COVID-19 negative polymerase chain reaction (PCR) were assessed for thyroid functions, IL-6, and Procalcitonin between moderate, severe, and critical pneumonia on HRCT. Results Seventy-five percent of patients with COVID-19 had thyroid abnormalities and higher IL-6 levels (76.10 ± 82.35 vs. 6.99 ± 3.99, 95% CI 52.18–100.01, P-value Conclusion This pilot study from Pakistan demonstrates that changes in serum TSH and TT3 levels may be important manifestations of the courses of COVID-19 pneumonia.
Databáze: OpenAIRE
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