In Vitro Activities of Six New Fluoroquinolones against Brucella melitensis
| Autor: | María José Fresnadillo, José Elías García-Sánchez, Enrique García-Sánchez, Isaı́as Montes Martı́nez, Ignacio Trujillano-Martı́n, José Angel García-Rodríguez |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Sitafloxacin
Colony Count Microbial Microbiology Anti-Infective Agents Moxifloxacin Brucella melitensis medicine heterocyclic compounds Pharmacology (medical) Antibacterial agent Pharmacology biology Chemistry biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Grepafloxacin Gatifloxacin Trovafloxacin Infectious Diseases Susceptibility bacteria Ofloxacin Fluoroquinolones medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 43:194-195 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.43.1.194 |
| Popis: | We have tested the in vitro activities of eight fluoroquinolones against 160 Brucella melitensis strains. The most active was sitafloxacin (MIC at which 90% of the isolates are inhibited [MIC 90 ], 0.12 μg/ml). In decreasing order, the activities (MIC 90 s) of the rest of the tested fluoroquinolones were as follows: levofloxacin, 0.5 μg/ml; ciprofloxacin, trovafloxacin, and moxifloxacin, 1 μg/ml; and ofloxacin, grepafloxacin, and gatifloxacin, 2 μg/ml. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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