Ossifying Pituitary Gonadotroph Adenoma: A Case Report
| Autor: | K. Liberopoulos, K. Kovacs, S. George, George Kontogeorgos, G. Zahariadis |
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| Rok vydání: | 1999 |
| Předmět: |
Adenoma
Male medicine.medical_specialty Pituitary gland endocrine system diseases Diagnosis Differential Pituitary adenoma Internal medicine medicine Humans Pituitary Neoplasms Aged Hypophysectomy Neuroradiology medicine.diagnostic_test Ossification business.industry Ossification Heterotopic Interventional radiology medicine.disease Prolactin stomatognathic diseases Treatment Outcome medicine.anatomical_structure Endocrinology Gonadotropins Pituitary Surgery Neurology (clinical) Neurosurgery medicine.symptom business |
| Zdroj: | Acta Neurochirurgica. 141:1001-1004 |
| ISSN: | 0942-0940 0001-6268 |
| DOI: | 10.1007/s007010050407 |
| Popis: | Bone formation in pituitary adenomas is a rare finding. Only two previous cases were published, occurring in a prolactin- producing and a growth hormone- producing pituitary adenoma respectively, both in pre-menopausal women.This is the third report of an ossified pituitary adenoma and the first report of a pituitary gonadotroph adenoma with bone formation occurring in an elderly man. MRI imaging revealed an unusual eggshell cap-like calcified structure surrounding the tumor. Histologically, the adenoma contained irregularly anastomosing trabecules with well formed lacunae and osteoblasts along the margins.Insufficient tumor blood supply may trigger proliferation of connective tissue that subsequently undergoes osteoid metaplasia. Pituitary adenoma with osteoid metaplasia should be included in the differential diagnosis of calcifying tumors in the sella region. |
| Databáze: | OpenAIRE |
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