Prion Diseases
| Autor: | John Collinge, Edward McKintosh, Sarah J. Tabrizi |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Prions animal diseases Bovine spongiform encephalopathy Scrapie Disease Prion Diseases Cellular and Molecular Neuroscience Species Specificity Virology mental disorders Epidemiology medicine Animals Humans Fatal familial insomnia business.industry Dietary exposure medicine.disease Gerstmann–Sträussler–Scheinker syndrome nervous system diseases Neurology Kuru Neurology (clinical) business |
| Zdroj: | Journal of Neurovirology. 9:183-193 |
| ISSN: | 1538-2443 1355-0284 |
| Popis: | Prion diseases are incurable neurodegenerative conditions affecting both animals and humans. They may be sporadic, infectious, or inherited in origin. Human prion diseases include Creutzfeldt-Jakob desease (CJD), Gerstmann-Straussler-Scheinker disease, kuru, and fatal familial insomnia. The appearance of variant CJD, and the demonstration that is caused by strains indistinguishable from bovine spongiform encephalopathy (BSE) in cattle, has led to the threat of a major epidemic of human prion disease in the UK and other countries where widespread dietary exposure to bovine prions has occurred. This article reviews the history and epidemiology of these diseases, and then focuses on important areas of current research in human prion disorders. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink