Pd-Catalyzed cascade cyclization of o-alkynylanilines via C-H/C-N bond cleavage leading to dibenzo[a,c]carbazoles

Autor:	Ma Hengmin, Yoshinori Yamamoto, Sheng Zhang, Hon Eong Ho, Ming Bao, Tienan Jin
Rok vydání:	2018
Předmět:	010405 organic chemistry Chemistry Carbazole Organic Chemistry Structural diversity 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Cascade Physical and Theoretical Chemistry Bond cleavage
Zdroj:	Organicbiomolecular chemistry. 16(29)
ISSN:	1477-0539
Popis:	A new and efficient Pd-catalyzed cascade cyclization of biaryl-tethered o-alkynylanilines for the formation of dibenzo[a,c]carbazole derivatives has been reported. The use of the alkyl-substituted tertiary anilines together with the combination of the PdCl2 catalyst with the MnO2 oxidant and PivOH is vital for giving rise to 5-endo cyclization, C–N bond cleavage, and C–H bond activation in a cascade manner to produce the corresponding products with structural diversity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae82b48c7128a0f0420106fc69bc32e https://pubmed.ncbi.nlm.nih.gov/29993085 Zobrazit plný text záznamu