High dose nicotinamide in the treatment of necrobiosis lipoidica
| Autor: | R.D.G. Peachey, Susan Handfield-Jones, S.K. Jones |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Niacinamide medicine.medical_specialty Erythema Dermatology Drug Administration Schedule Necrobiosis lipoidica chemistry.chemical_compound medicine Humans Aged Nicotinamide Necrobiosis Lipoidica business.industry Middle Aged medicine.disease Open study Diabetes Mellitus Type 1 chemistry Female medicine.symptom business Diabetic control |
| Zdroj: | The British journal of dermatology. 118(5) |
| ISSN: | 0007-0963 |
| Popis: | An open study of high dose nicotinamide in the treatment of 15 patients with necrobiosis lipoidica is reported. Of 13 patients who remained on treatment for more than 1 month, eight improved. Improvement took the form of a decrease in pain and soreness, a decrease in erythema and the healing of ulcers if present, although the skin did not return completely to normal in any patient. There were no significant side-effects, particularly with respect to diabetic control, an important finding as lesions tended to relapse if treatment was stopped. |
| Databáze: | OpenAIRE |
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