Case Report: Management Approach and Use of Extracorporeal Membrane Oxygenation for Diffuse Alveolar Hemorrhage After Pediatric Hematopoietic Cell Transplant
| Autor: | Samir Shah, Hitesh S. Sandhu, Caitlin Hurley, Asya Agulnik, Michael J. McNeil, Saad Ghafoor, Ronald Ray R.R. Morrison, Amr Qudeimat, Kimberly Fan, Sara M. Federico, Arun Saini, Jennifer McArthur |
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| Rok vydání: | 2021 |
| Předmět: |
diffuse alveolar hemorrhage (DAH)
medicine.medical_treatment Case Report Context (language use) pediatric acute respiratory distress syndrome Pediatrics extracorporeal life support (ECLS) 03 medical and health sciences 0302 clinical medicine Refractory 030225 pediatrics Extracorporeal membrane oxygenation Medicine Hematopoietic cell business.industry Pulmonary Complication lcsh:RJ1-570 lcsh:Pediatrics Diffuse alveolar hemorrhage Transplantation extracorporeal mebrane oxygenation surgical procedures operative hematopoitic stem cell transplantation 030228 respiratory system Respiratory failure Anesthesia Pediatrics Perinatology and Child Health business |
| Zdroj: | Frontiers in Pediatrics, Vol 8 (2021) Frontiers in Pediatrics |
| ISSN: | 2296-2360 |
| Popis: | Introduction: Diffuse alveolar hemorrhage (DAH) is an early pulmonary complication of hematopoietic cell transplantation (HCT) associated with severe hypoxemic respiratory failure and mortality. Extracorporeal membrane oxygenation (ECMO) support is often used for respiratory failure refractory to conventional interventions; however, its use has been limited in HCT patients with DAH due to potential for worsening alveolar hemorrhage and reported high mortality.Case Presentation: We report two cases of DAH following HCT who developed refractory hypoxemic respiratory failure despite cessation of bleeding and were successfully supported with ECMO.Conclusion: DAH after HCT should not automatically preclude ECMO support; rather, these patients must be evaluated individually for ECMO within the context of their overall clinical picture. |
| Databáze: | OpenAIRE |
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