Mycobacterium tuberculosis retains viability in RNAlater buffer but not in GTC-TCEP and DNA/RNA Shield

Autor: L. Krausser, S.M. Braet, Z. Benaamar, M. Van Dyck-Lippens, B.C. de Jong, L. Rigouts
Rok vydání: 2023
Předmět:
Zdroj: Diagnostic microbiology and infectious disease
ISSN: 0732-8893
Popis: Efficient inactivation of clinical samples containing mycobacteria is crucial for biosafety during shipment and handling. When stored in RNAlater, Mycobacterium tuberculosis H37Ra remains viable, and our results sug-gest that at-20 degrees C and 4 degrees C changes in the mycobacterial transcriptome are possible. Only GTC-TCEP and DNA/RNA Shield inactivate sufficiently for shipment.
Databáze: OpenAIRE