Prediction of abortion using three-dimensional ultrasound volumetry of the gestational sac and the amniotic sac in threatened abortion
| Autor: | V. Grinin, Marwan Odeh, Mohamad Kais, Rene Tendler, Ella Ophir, Jacob Bornstein |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Gestational sac Amniotic sac Gestational Age Abortion Sensitivity and Specificity Ultrasonography Prenatal Young Adult Pregnancy medicine Humans Radiology Nuclear Medicine and imaging Vaginal bleeding Amnion Gynecology Obstetrics business.industry Area under the curve Gestational age Organ Size Middle Aged medicine.disease Abortion Threatened Abortion Spontaneous Pregnancy Trimester First medicine.anatomical_structure Gestational Sac ROC Curve embryonic structures Gestation Female medicine.symptom business |
| Zdroj: | Journal of Clinical Ultrasound. 40:389-393 |
| ISSN: | 0091-2751 |
| DOI: | 10.1002/jcu.21957 |
| Popis: | Purpose. To determine whether gestational sac volume (GSV) or amniotic sac volume (ASV) and/or the difference between them can predict abortion in women with first-trimester threatened abortion. Methods. Ninety patients between 6 and 12 weeks of gestation presenting with vaginal bleeding were studied. Seventy-six delivered after 24 weeks of gestation (group A) and 14 aborted before 20 weeks of gestation (group B). All patients had a singleton viable pregnancy demonstrated by transvaginal ultrasound. Gestational sac and amniotic sac volumes were measured in all the patients using three-dimensional transvaginal ultrasound with Virtual Organ Computer-aided Analysis software, and the gestational sac volume − amniotic sac volume (GSV − ASV) was calculated. Results. The groups did not differ in terms of age, parity, number of previous abortions, or term deliveries. The GSV (group A: mean 32.0 ± 27.7 cm3; group B: 26.7 ± 29.1 cm3) and the ASV (group A: 21.1 ± 25.5 cm3; group B: 20.6 ± 26.0 cm3) were not statistically different, while the GSV − ASV was significantly smaller in group B (aborting before week 20) (group A: 10.9 ± 10.9 cm3; group B: 6.1 ± 8.6 cm3; p < 0.05). Using receiver operator curves, the area under the curve for predicting normal pregnancy outcome of the GSV − ASV measurement was 0.654. When the GSV − ASV was 1.8 cm3 or less, abortion was predicted with 84% sensitivity and 43% specificity. Conclusions. The measurement of the GSV and the ASV are not good predictors of abortion in patients with first-trimester vaginal bleeding, whereas the use of the GSV − ASV may be helpful in predicting the outcome of pregnancy. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound 40:389–393, 2012 |
| Databáze: | OpenAIRE |
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