Inhibition of Tumor Promotion by a Biomimetic Superoxide Dismutase
| Autor: | Walter J. Kozumbo, Donna M. Bush, Thomas W. Kensler |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
chemistry.chemical_classification
Reactive oxygen species Skin Neoplasms Multidisciplinary Papilloma biology Superoxide Dismutase Superoxide Antineoplastic Agents Ornithine Decarboxylase Inhibitory postsynaptic potential Salicylates Superoxide dismutase Mice chemistry.chemical_compound chemistry Biochemistry Mouse Epidermis Carcinogens biology.protein Animals Tetradecanoylphorbol Acetate Female Tumor promotion |
| Zdroj: | Science. 221:75-77 |
| ISSN: | 1095-9203 0036-8075 |
| DOI: | 10.1126/science.6857269 |
| Popis: | A low molecular weight, lipophilic, copper coordination complex with superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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