Controlled trial of ketorolac in tension-type headache
| Autor: | R. N. Harden, R. H. Gracely, K. Fink, D. Rogers |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Meperidine Visual analogue scale medicine.medical_treatment Analgesic Neurological disorder Placebo Injections Intramuscular Promethazine law.invention Randomized controlled trial law Surveys and Questionnaires medicine Humans Tolmetin Saline Pain Measurement Analysis of Variance business.industry Tension-Type Headache Analgesics Non-Narcotic Middle Aged medicine.disease Surgery Ketorolac Anesthesia Female Neurology (clinical) business medicine.drug |
| Zdroj: | Neurology. 50:507-509 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/wnl.50.2.507 |
| Popis: | Intramuscular ketorolac 60 mg, meperidine 50 mg plus promethazine 25 mg, and normal saline were compared in acute exacerbations of tension-type headache. Forty-one subjects (30 females and 11 males) were randomized into three groups and evaluated by the McGill Short-Form Pain Questionnaire before treatment, and 0.5, 1, 2, 3, 4, 5, and 6 hours after treatment. All three groups showed a significant treatment effect that persisted for the 6 hours of evaluation. Ketorolac treatment was significantly better than placebo at 0.5 and 1 hour by the Visual Analog Scale (VAS) and Pain Rating Index, and better than meperidine at 2 hours (by the VAS). Meperidine and placebo did not differ at any time point. Ketorolac is effective in short-term treatment of tension-type headache. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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