Fat tissue morphology of long-term sex steroid deficiency and estrogen treatment in female rats
| Autor: | Aline de Sousa dos Santos, Carlos Alberto Soares da Costa, Gabrielle de Paula Lopes Gonzalez, Mariana dos Santos Ribeiro, Jorge José de Carvalho, Celly Cristina Alves do Nascimento Saba, Aluana C. Santana, Luciana Armada |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class medicine.medical_treatment Abdominal Fat Adipose tissue Time Steroid chemistry.chemical_compound Internal medicine medicine Animals Rats Wistar Mass gain Adiposity Estradiol biology Obstetrics and Gynecology Estrogens Rats Fibronectin Vascular endothelial growth factor Treatment Outcome Endocrinology Reproductive Medicine chemistry Estrogen Sex steroid biology.protein Female Estradiol treatment hormones hormone substitutes and hormone antagonists |
| Zdroj: | Fertility and Sterility. 95:1478-1481 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/j.fertnstert.2011.01.020 |
| Popis: | After long-term estradiol deficiency, female rats displayed body mass gain accompanied by an increase in the size of adipocytes, an increase in hyperglycemia, and a decrease in insulinemia. The effects were reversed by daily estradiol treatment. Adiposity was suggested by the increased vascular endothelial growth factor expression in castrated rats, whereas the proliferative effect of estradiol was suggested by the increased fibronectin expression in treated rats. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|