Biochemical effects of sulfuric acid mist inhalation by human subjects while at rest
Autor: | Keith E. Muller, Wendy Blomquist, Suzanne Chaney, Paulette DeWitt |
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Rok vydání: | 1980 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent Rest Glutathione reductase Transaminase chemistry.chemical_compound Blood serum Oxaloacetic acid Internal medicine medicine Environmental Chemistry Humans General Environmental Science Aerosols Inhalation Public Health Environmental and Occupational Health Glutathione Sulfuric Acids Red blood cell medicine.anatomical_structure Endocrinology Blood chemistry Biochemistry Lysozyme |
Zdroj: | Archives of environmental health. 35(5) |
ISSN: | 0003-9896 |
Popis: | This study evaluated the effect of sulfuric acid aerosol exposure for 2 consecutive days on seven human biochemical blood parameters. A total of 20 human subjects were exposed to 100 micrograms/m3 (0.033 microM) sulfuric acid aerosol (0.5 microns mean mass diameter) for 4 hr/day for 2 consecutive days. A total of 17 human subjects were exposed to 4 hr of ambient air on both exposure days. The chemical blood parameters were measured pre- and post-exposure, and 20 hr after the second exposure: serum glutathione, red blood cell glutathione reductase, red blood cell glucose-6-phosphate dehydrogenase, lysozyme, serum glutamic oxaloacetic acid transaminase, serum vitamin E, and 2, 3-diphosphoglycerate. The results indicate no significant response in any of the seven biochemical blood parameters measured. At this level, repeated exposure did not over-burden the upper airway defenses against acid aerosol. |
Databáze: | OpenAIRE |
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