Capillarity and Mitochondrial Distribution in Rat Myocardium Following Exercise Training
| Autor: | K. E. Conley, S. R. Kayar, H. Claassen, Hans-Heinrich Hoppeler |
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| Rok vydání: | 1986 |
| Předmět: |
Male
medicine.medical_specialty Physiology Cardiac Volume Mitochondrial distribution Physical Exertion Aquatic Science Mitochondria Heart Volume density Running Adenosine Triphosphate Oxygen Consumption Internal medicine medicine Animals Molecular Biology Ecology Evolution Behavior and Systematics Chemistry VO2 max Rats Inbred Strains Anatomy Coronary Vessels Capillaries Rats Endocrinology Capillary length Capillary density Insect Science Circulatory system Heart mass Animal Science and Zoology Rat myocardium |
| Zdroj: | Journal of Experimental Biology. 120:189-199 |
| ISSN: | 1477-9145 0022-0949 |
| DOI: | 10.1242/jeb.120.1.189 |
| Popis: | Rats were subjected to a laddermill running programme either once per week for 6 weeks, or daily for 6 weeks. Heart mass and maximal oxygen consumption rate increased relative to controls and with the frequency of the running programme. Mitochondrial distribution, measured in seven regions within fibres, was similar in all hearts, with a peak volume density of 0·42 ±0·01 occurring 4–5 μm from the centre of a capillary. Capillary density decreased with increasing heart mass, but total capillary length and capillary-to-fibre ratio were constant. Thus the higher metabolic demands of the running programmes did not alter the volume density or distribution of mitochondria, despite significant increases in heart mass and decreases in capillarity. |
| Databáze: | OpenAIRE |
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