Organising pneumonia can be the inaugural manifestation in connective tissue diseases, including Sjögren's syndrome
Autor: | Bruno Crestani, Sylvain Marchand-Adam, Elisabeth Diot, Patrice Diot, A.-C. Henriet, O. Favelle, A de Muret |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Pathology Fatal outcome Connective tissue Context (language use) Case Reports Disease organising pneumonia Fatal Outcome medicine Humans Connective Tissue Diseases Connective tissue disease Aged lcsh:RC705-779 business.industry lcsh:Diseases of the respiratory system medicine.disease Dermatology Organising pneumonia Sjogren's Syndrome medicine.anatomical_structure Cryptogenic Organizing Pneumonia Rheumatoid arthritis Female Sjögren's syndrome Sjogren s business |
Zdroj: | European Respiratory Review, Vol 19, Iss 116, Pp 161-163 (2010) Eur Respir Rev |
ISSN: | 1600-0617 0905-9180 |
DOI: | 10.1183/09059180.00002410 |
Popis: | Connective tissue diseases are known to be one of the causes of organising pneumonia (OP). However, this association is rare and signs of OP usually occur in the context of an already diagnosed disease. We report three cases of OP preceding the articular symptoms of the underlying connective tissue disease by 3–6 months in two cases of rheumatoid arthritis and by 36 months in one patient with primary Sjögren's syndrome. The diagnosis of post-infectious OP had initially been suspected in the three cases and the patients had not been followed up further. The occurrence of OP preceding articular or any other extrapulmonary involvement of connective tissue disease had been reported in only four cases in the literature and, to our knowledge, no case preceding Sjögren's syndrome had ever been reported. These observations suggest that exhaustive investigations should be considered when OP is diagnosed, including antinuclear auto-antibodies and investigations for Sjögren's syndrome, even when there are no clinical signs suggesting an underlying connective tissue disease. These investigations should also be repeated during the course of the disease, especially in the case of OP continuing to progress under treatment and, of course, if signs of connective tissue disease appear. |
Databáze: | OpenAIRE |
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