Optimal Broadband Noise Matching to Inductive Sensors: Application to Magnetic Particle Imaging

Autor: Greig C. Scott, Di Xiao, Neerav Dixit, Beliz Gunel, Steven M. Conolly, Bo Zheng, Patrick W. Goodwill, Wencong Zhang, Kuan Lu
Rok vydání: 2017
Předmět:
Zdroj: IEEE Transactions on Biomedical Circuits and Systems. 11:1041-1052
ISSN: 1940-9990
1932-4545
Popis: Inductive sensor-based measurement techniques are useful for a wide range of biomedical applications. However, optimizing the noise performance of these sensors is challenging at broadband frequencies, owing to the frequency-dependent reactance of the sensor. In this work, we describe the fundamental limits of noise performance and bandwidth for these sensors in combination with a low-noise amplifier. We also present three equivalent methods of noise matching to inductive sensors using transformer-like network topologies. Finally, we apply these techniques to improve the noise performance in magnetic particle imaging, a new molecular imaging modality with excellent detection sensitivity. Using a custom noise-matched amplifier, we experimentally demonstrate an 11-fold improvement in noise performance in a small animal magnetic particle imaging scanner.
Databáze: OpenAIRE