Left Ventricular Compliance and Abnormally Contracting Segments in Postmyocardial Infarction Patients
| Autor: | Charles E. Rackley, Bolling J. Feild, Richard O. Russell, McKamy Smith |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Pulmonary and Respiratory Medicine
Cardiac Catheterization medicine.medical_specialty Time Factors Cardiac Volume Heart Ventricles medicine.medical_treatment Myocardial Infarction Diastole Infarction Blood Pressure Critical Care and Intensive Care Medicine Perimeter Electrocardiography Heart Rate Internal medicine Methods Humans Medicine Myocardial infarction Cardiac catheterization Body surface area business.industry Angiocardiography Heart Stroke volume medicine.disease Compliance (physiology) Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Chest. 65:368-378 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.65.4.368 |
| Popis: | The relationships between left ventricular (LV) compliance, the magnitude of LV segmental disease assessed by the size of abnormally contracting segments (ACS), and ventricular size measured by ventricular volumes were examined in 38 patients who were studied by cardiac catheterization and LV biplane angiography (6-12 films/sec) within one year following myocardial infarction. LV compliance was assessed by four formulae: ΔV/ΔP (angio stroke volume/LV end-diastolic minus lowest early diastolic pressure); ΔV/ESV/ΔP (ESV = end-systolic volume); dV/dP ED and dV/dP ED × 1/end-diastolic volume/body surface area; percentage of ACS was measured as the akinetic or dyskinetic length along the end-diastolic perimeter on biplane LV angiograms, expressed as a percentage of the total LV diastolic perimeter. Of the four indices of compliance, ΔV/ESV/ΔP was found to have the highest correlation with percentage of ACS (r 2 = .695, P = 1.5 × 10 −6 ). This correlation (ΔV/ESV/ΔP versus percentage of ACS) was higher than the correlation between percentage of ACS and any single volume or pressure parameter. The relationship between ΔV/ESV/ΔP and percentage of ACS was significantly higher than the correlation between ΔV/ESV/ΔP and end-diastolic volume (r 2 = .416, P = .002), the latter correlation primarily being due to mathematical relationships. Values for ACS above 8 percent were associated with ΔV/ESV/ΔP values which were below those obtained for normal subjects and below a theoretical normal range for ΔV/ESV/ΔP. These data suggest that left ventricular compliance is sensitive to the magnitude of LV segmental disease and is influenced less by changes in ventricular size in postmyocardial infarction patients. |
| Databáze: | OpenAIRE |
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