Outcome measures for Alzheimer's disease:A global inter-societal Delphi consensus
| Autor: | Tim S. Ellison, Stefano F. Cappa, Dawne Garrett, Jean Georges, Takeshi Iwatsubo, Joel H. Kramer, Maryna Lehmann, Constantine Lyketsos, Andrea B. Maier, Jennifer Merrilees, John C. Morris, Sharon L. Naismith, Flavio Nobili, Marco Pahor, Dimity Pond, Louise Robinson, Pinar Soysal, Mathieu Vandenbulcke, Christopher J. Weber, Pieter Jelle Visser, Michael Weiner, Giovanni B. Frisoni |
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| Přispěvatelé: | RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Psychology 6 |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
MILD COGNITIVE IMPAIRMENT
Epidemiology Health Policy measures Alzheimer's disease outcomes Delphi FUNCTIONAL-ACTIVITIES QUESTIONNAIRE DEPRESSION SCALE Psychiatry and Mental health Cellular and Molecular Neuroscience NEUROPSYCHIATRIC INVENTORY CORNELL SCALE Developmental Neuroscience consensus QUALITY-OF-LIFE DAILY LIVING SCALE Neurology (clinical) Geriatrics and Gerontology OLDER-ADULTS INSTRUMENTAL-ACTIVITIES dementia REVISED ACE-R |
| Zdroj: | Ellison, T S, Cappa, S F, Garrett, D, Georges, J, Iwatsubo, T, Kramer, J H, Lehmann, M, Lyketsos, C, Maier, A B, Merrilees, J, Morris, J C, Naismith, S L, Nobili, F, Pahor, M, Pond, D, Robinson, L, Soysal, P, Vandenbulcke, M, Weber, C J, Visser, P J, Weiner, M & Frisoni, G B 2023, ' Outcome measures for Alzheimer's disease : A global inter-societal Delphi consensus ', Alzheimer's and Dementia, vol. 19, no. 6, pp. 2707-2729 . https://doi.org/10.1002/alz.12945 Alzheimer's & Dementia. Elsevier Science |
| ISSN: | 1552-5260 |
| DOI: | 10.1002/alz.12945 |
| Popis: | Introduction: We aim to provide guidance on outcomes and measures for use in patients with Alzheimer's clinical syndrome. Methods: A consensus group of 20 voting members nominated by 10 professional societies, and a non-voting chair, used a Delphi approach and modified GRADE criteria. Results: Consensus was reached on priority outcomes (n = 66), measures (n = 49) and statements (n = 37) across nine domains. A number of outcomes and measurement instruments were ranked for: Cognitive abilities; Functional abilities/dependency; Behavioural and neuropsychiatric symptoms; Patient quality of life (QoL); Caregiver QoL; Healthcare and treatment-related outcomes; Medical investigations; Disease-related life events; and Global outcomes. Discussion: This work provides indications on the domains and ideal pertinent measurement instruments that clinicians may wish to use to follow patients with cognitive impairment. More work is needed to develop instruments that are more feasible in the context of the constraints of clinical routine. |
| Databáze: | OpenAIRE |
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