The impact of African American race on prostate cancer detection on repeat prostate biopsy in a veteran population
| Autor: | Joseph P. Weiner, Jeffrey P. Weiss, Komal Mehta, David Schreiber, William A. Sterling |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Image-Guided Biopsy
Male medicine.medical_specialty Prostate biopsy Urology Population 030232 urology & nephrology Veterans Health 03 medical and health sciences Prostate cancer 0302 clinical medicine Prostate Biopsy medicine Humans education Aged Retrospective Studies Ultrasonography Prostatic Intraepithelial Neoplasia Gynecology education.field_of_study PSA Velocity Atypical small acinar proliferation Intraepithelial neoplasia medicine.diagnostic_test business.industry Incidence Biopsy Needle Prostatic Neoplasms Organ Size Middle Aged Prostate-Specific Antigen medicine.disease United States Black or African American medicine.anatomical_structure Nephrology 030220 oncology & carcinogenesis Neoplasm Grading business |
| Zdroj: | International Urology and Nephrology. 48:2015-2021 |
| ISSN: | 1573-2584 0301-1623 |
| DOI: | 10.1007/s11255-016-1407-8 |
| Popis: | Racial differences in the incidence of prostate cancer on initial biopsy are well established, but the predictive value of African American race on the probability of prostate cancer detection on repeat biopsy is unknown. At a single institution between January 2007 and June 2014, we reviewed 277 men who first underwent a negative transrectal ultrasound guided needle biopsy of the prostate, and who then subsequently underwent a second biopsy. Detection rates were compared via Chi-square analysis. Race, age, PSA, presence of high-grade prostatic intraepithelial neoplasia, presence of atypical small acinar proliferation, prostate volume, PSA velocity and PSA density were compared via a multivariate logistic regression analysis. 496 AA men and 352 Caucasian men underwent initial biopsy, and AA men had a 49 % cancer detection rate, compared to 34 % in Caucasians (p |
| Databáze: | OpenAIRE |
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