Effect of Amplitude Spectral Area on Termination of Fibrillation and Outcomes in Pediatric Cardiac Arrest

Autor: Annemarie Silver, Sandeep V. Pandit, Tia T Raymond, Dianne L. Atkins, Dana Niles, Heather Griffis, Xuemei Zhang, Richard Hanna, Vinay M. Nadkarni, Sarah E. Haskell, Javier J. Lasa
Rok vydání: 2021
Předmět:
Male
Time Factors
medicine.medical_treatment
030204 cardiovascular system & hematology
Arrhythmias
Sudden Cardiac Death
Electrocardiography
0302 clinical medicine
Risk Factors
Arrhythmia and Electrophysiology
Hospital Mortality
Child
Original Research
Age Factors
defibrillation
Europe
Cardiopulmonary Arrest
Amplitude
Treatment Outcome
Child
Preschool
Cardiology
Female
medicine.symptom
Return of Spontaneous Circulation
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Canada
Adolescent
pediatrics
Defibrillation
Electric Countershock
Return of spontaneous circulation
Risk Assessment
cardiopulmonary resuscitation
03 medical and health sciences
Predictive Value of Tests
Internal medicine
medicine
Humans
Cardiopulmonary resuscitation
Retrospective Studies
Fibrillation
Cardiopulmonary Resuscitation and Emergency Cardiac Care
business.industry
Infant
030208 emergency & critical care medicine
medicine.disease
ventricular fibrillation
United States
Heart Arrest
Ventricular fibrillation
business
Defibrillators
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
ISSN: 2047-9980
Popis: Background Amplitude spectral area (AMSA) predicts termination of fibrillation (TOF) with return of spontaneous circulation (ROSC) and survival in adults but has not been studied in pediatric cardiac arrest. We characterized AMSA during pediatric cardiac arrest from a Pediatric Resuscitation Quality Collaborative and hypothesized that AMSA would be associated with TOF and ROSC. Methods and Results Children aged 20 minutes without chest compressions. Univariate and multivariable logistic regression analyses controlling for weight, current, and illness category were performed. Primary end points were TOF and ROSC. Secondary end points were 24‐hour survival and survival to discharge. Between 2015 and 2019, 50 children from 14 hospitals with 111 shocks were identified. In univariate analyses AMSA was not associated with TOF and AMS‐Aavg was not associated with ROSC. Multivariable logistic regression showed no association between AMSA and TOF but controlling for defibrillation average current and illness category, there was a trend to significant association between AMSA‐avg and ROSC (odds ratio, 1.10 [1.00‒1.22] P =0.058). There was no significant association between AMSA‐avg and 24‐hour survival or survival to hospital discharge. Conclusions In pediatric patients, AMSA was not associated with TOF, whereas AMSA‐avg had a trend to significance for association in ROSC, but not 24‐hour survival or survival to hospital discharge. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02708134.
Databáze: OpenAIRE
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