Effect of Amplitude Spectral Area on Termination of Fibrillation and Outcomes in Pediatric Cardiac Arrest
Autor: | Annemarie Silver, Sandeep V. Pandit, Tia T Raymond, Dianne L. Atkins, Dana Niles, Heather Griffis, Xuemei Zhang, Richard Hanna, Vinay M. Nadkarni, Sarah E. Haskell, Javier J. Lasa |
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Rok vydání: | 2021 |
Předmět: |
Male
Time Factors medicine.medical_treatment 030204 cardiovascular system & hematology Arrhythmias Sudden Cardiac Death Electrocardiography 0302 clinical medicine Risk Factors Arrhythmia and Electrophysiology Hospital Mortality Child Original Research Age Factors defibrillation Europe Cardiopulmonary Arrest Amplitude Treatment Outcome Child Preschool Cardiology Female medicine.symptom Return of Spontaneous Circulation Cardiology and Cardiovascular Medicine medicine.medical_specialty Canada Adolescent pediatrics Defibrillation Electric Countershock Return of spontaneous circulation Risk Assessment cardiopulmonary resuscitation 03 medical and health sciences Predictive Value of Tests Internal medicine medicine Humans Cardiopulmonary resuscitation Retrospective Studies Fibrillation Cardiopulmonary Resuscitation and Emergency Cardiac Care business.industry Infant 030208 emergency & critical care medicine medicine.disease ventricular fibrillation United States Heart Arrest Ventricular fibrillation business Defibrillators |
Zdroj: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
ISSN: | 2047-9980 |
Popis: | Background Amplitude spectral area (AMSA) predicts termination of fibrillation (TOF) with return of spontaneous circulation (ROSC) and survival in adults but has not been studied in pediatric cardiac arrest. We characterized AMSA during pediatric cardiac arrest from a Pediatric Resuscitation Quality Collaborative and hypothesized that AMSA would be associated with TOF and ROSC. Methods and Results Children aged 20 minutes without chest compressions. Univariate and multivariable logistic regression analyses controlling for weight, current, and illness category were performed. Primary end points were TOF and ROSC. Secondary end points were 24‐hour survival and survival to discharge. Between 2015 and 2019, 50 children from 14 hospitals with 111 shocks were identified. In univariate analyses AMSA was not associated with TOF and AMS‐Aavg was not associated with ROSC. Multivariable logistic regression showed no association between AMSA and TOF but controlling for defibrillation average current and illness category, there was a trend to significant association between AMSA‐avg and ROSC (odds ratio, 1.10 [1.00‒1.22] P =0.058). There was no significant association between AMSA‐avg and 24‐hour survival or survival to hospital discharge. Conclusions In pediatric patients, AMSA was not associated with TOF, whereas AMSA‐avg had a trend to significance for association in ROSC, but not 24‐hour survival or survival to hospital discharge. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02708134. |
Databáze: | OpenAIRE |
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