Effects of neonatal anoxia on maze learning in rats
| Autor: | John W. Richardson |
|---|---|
| Rok vydání: | 1954 |
| Předmět: |
Oxygen deprivation
Fetus medicine.medical_specialty Asphyxia Neonatorum business.industry Neonatal anoxia Maze learning Prior learning Uterus Infant Newborn General Biochemistry Genetics and Molecular Biology Surgery Rats medicine.anatomical_structure Anesthesia Respiration Medicine Animals Humans Learning business Hypoxia Maze Learning Full Term |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 86(2) |
| ISSN: | 0037-9727 |
| Popis: | Summary and ConclusionsPeriods of anoxia ranging from 1 to 20 minutes were induced in unborn rats by preventing the initiation of respiration before removing the full term fetuses from the uterus. Beginning at 65 days of age, the experimental and control animals were tested on the Hebb-Williams closed maze. In a series of 12 standardized tests the experimental rats made more errors than the controls (p = .06). The inferiority of anoxic animals was most marked in the final set of 6 tests during which they were significantly inferior to the control group (p = .04). Control rats displayed progressive improvement in performance in successive maze problems, but no such improvement was evident in the records of experimental cases. It appears that oxygen deprivation at the time of birth tends to reduce the rat's ability to transfer prior learning to new situations. Within the experimental group, however, there was no relationship between the duration of the anoxic period and the extent of deterioration in maze p... |
| Databáze: | OpenAIRE |
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