Device related thrombus after left atrial appendage closure: State of the art
| Autor: | Yuan Bai, Li-Sheng Jiang, Jiangtao Yu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
030204 cardiovascular system & hematology law.invention 03 medical and health sciences 0302 clinical medicine Postoperative Complications Randomized controlled trial law Left atrial Internal medicine Atrial Fibrillation medicine Humans In patient Atrial Appendage cardiovascular diseases 030212 general & internal medicine Thrombus Cardiac Surgical Procedures Stroke business.industry Incidence (epidemiology) Atrial fibrillation Thrombosis General Medicine Prostheses and Implants medicine.disease Stroke prevention Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pacing and clinical electrophysiology : PACEREFERENCES. 44(7) |
| ISSN: | 1540-8159 |
| Popis: | Atrial fibrillation (AF), the most common arrhythmia, is a major cause of stroke and systemic embolism. Patients with AF are at higher risk of stroke with the left atrial appendage (LAA) being the most common site for thrombus formation. Although oral anticoagulation (OAC) remains the standard of care for stroke prevention in AF patients, there are still several limitations, including increased risk of bleeding and noncompliance. LAA closure (LAAC) has been found to be non-inferior to OAC in preventing all-cause strokes and systemic embolisms in randomized clinical trials, and is increasingly performed for stroke prevention in patients with nonvalvular AF (NVAF). However, device-related thrombus (DRT) after LAAC and a potentially increased risk of stroke related to DRT were observed in several registered studies, and attract wide concern. This review provides a comprehensive update on the incidence, mechanism, risk factors, prevention, diagnosis, and treatment of DRT after LAAC in patients with NVAF. |
| Databáze: | OpenAIRE |
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