Mechanisms of food allergy
| Autor: | Philippe Eigenmann |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Allergy Intestinal Mucosa/*immunology Arachis Allergens/*immunology Immunoglobulin E/blood Disease Immunoglobulin E T-Lymphocytes Regulatory Immunopathology Egg Proteins/immunology Eosinophilic Immunology and Allergy Mast Cells Intestinal Mucosa Sensitization T-Lymphocytes Regulatory/*immunology Arachis hypogaea/immunology ddc:618 biology Peanut Hypersensitivity/diagnosis/*immunology digestive oral and skin physiology Milk/immunology Breast Feeding Milk medicine.anatomical_structure Cytokines Mast Cells/immunology Proctocolitis Immunology Milk Hypersensitivity/diagnosis/*immunology Cytokines/immunology Food allergy medicine Animals Humans Peanut Hypersensitivity Egg Hypersensitivity/diagnosis/*immunology Platelet Activating Factor Egg Hypersensitivity Eosinophils/immunology business.industry Platelet Activating Factor/immunology Egg Proteins Infant Newborn Infant Allergens medicine.disease Eosinophils Pediatrics Perinatology and Child Health biology.protein Milk Hypersensitivity business |
| Zdroj: | Pediatric Allergy and Immunology, Vol. 20, No 1 (2009) pp. 5-11 |
| ISSN: | 1399-3038 0905-6157 |
| Popis: | Allergy type sensitization occurring in the gut results from a break in oral tolerance, mostly occurring in early childhood. In these patients, a minute amount of the large load of potential food allergens not only will result in immunoglobulin E (IgE) type sensitization mostly, but also in food allergies resulting from other mechanisms including eosinophil-driven disease or resulting from T-cell-mediated inflammation. Symptoms elicited by subsequent exposure to foods in these patients will be mostly in relation to the mechanism of the disease. In this educational review series, we described three cases of food allergy, first, a child with typical IgE-mediated food allergy, second, a child with eosinophilic proctocolitis and in the third patient, we will address tolerance acquisition mechanisms. These cases are discussed with regards to their specific immune events. |
| Databáze: | OpenAIRE |
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