A study on the seasonal variation of the essential oil composition from Plectranthus hadiensis and its antibacterial activity
| Autor: | Raju Sripathi, Subban Ravi, Dharani Jayagopal |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Drug Evaluation
Preclinical India Plant Science Cyclohexane Monoterpenes Microbial Sensitivity Tests 01 natural sciences Biochemistry Gas Chromatography-Mass Spectrometry Analytical Chemistry law.invention chemistry.chemical_compound law Botany medicine Oils Volatile Plant Oils Plectranthus Chemical composition Essential oil biology 010405 organic chemistry Organic Chemistry Seasonality biology.organism_classification medicine.disease Fenchone 0104 chemical sciences Anti-Bacterial Agents Monocyclic Sesquiterpenes 010404 medicinal & biomolecular chemistry chemistry Monoterpenes Lamiaceae Composition (visual arts) Seasons Plectranthus hadiensis Antibacterial activity Sesquiterpenes |
| DOI: | 10.6084/m9.figshare.5285218.v1 |
| Popis: | The chemical composition and seasonal variation of the essential oil from the aerial parts of Plectranthus hadiensis grown during the rainy and summer seasons in the Western Ghats of India was analysed by GC–MS technique. The analysis of rainy season oil led to the identification of 31 compounds, representing 96.4% of the essential oil and the winter season oil led to 25 compounds, representing 95.1% of the oil. Most of the compounds were sesquiterpenes and oxygenated monoterpenes. The major components of the rainy season oil were L-fenchone (30.42%), β-farnesene (11.87%), copaene(11.10%), 2,3-dimethyl hydroquinone (10.78%), α-caryophyllene(8.41%) and piperitone oxide (3.94%) and of the summer season oil are L-fenchone (31.55%), copaene(11.93%), β-farnesene (10.45%), 1,8-naphthalenedione, 8a-ethylperhydro (10.06%), α-caryophyllene(6.36%), piperitone oxide (5.79%) and limonene(4.63%). Antibacterial activity of the essential oil of P. hadiensis was tested using zone of inhibition and minimum inhibition concentration methods. Both the oils inhibited the organisms and showed the zone of inhibition in the range of 20–35 mm with MIC values between 32 and 64 mg/dL. |
| Databáze: | OpenAIRE |
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