Bovine Brucellosis in Gauteng, South Africa: Seroprevalence amongst Cattle Handlers and Variables Associated with Seropositive Cattle Herds, 2014–2016
| Autor: | D.A. Abernethy, Jennifer Rossouw, Eric Etter, Krpasha Govindasamy, Peter N. Thompson, Bernice Nerine Harris |
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| Přispěvatelé: | University of Pretoria [South Africa], National Institute for Communicable Diseases [Johannesburg] (NICD), Aberystwyth University, Animal, Santé, Territoires, Risques et Ecosystèmes (UMR ASTRE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), This research was jointly funded by the University of Pretoria Animal and Zoonotic Diseases Institutional Research Theme (AZD IRT) and by the South African Health and Welfare Sector Education and Training Authority (HWSETA) and the APC was funded by University of Pretoria. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Veterinary medicine
[SDV]Life Sciences [q-bio] animal diseases Herd health L73 - Maladies des animaux 0403 veterinary science Bovine brucellosis South Africa 0302 clinical medicine Facteur de risque Brucellose Immunology and Allergy Medicine RBT ® BrucellaCapt ® 2. Zero hunger seroprevalence 04 agricultural and veterinary sciences 3. Good health Travailleur agricole Infectious Diseases risk factor brucellosis veterinary official S50 - Santé humaine cattle handler BrucellaCapt® IgG ELISA® IgM ELISA® RBT® B. abortus IgM ELISA ® Microbiology (medical) 040301 veterinary sciences 030231 tropical medicine Article 03 medical and health sciences Maladie de l'homme Seroprevalence Farm workers Surveillance épidémiologique Risk factor Igg elisa Molecular Biology IgG ELISA ® Transmission des maladies Bovin General Immunology and Microbiology business.industry Brucellosis medicine.disease Enquête pathologique Herd business |
| Zdroj: | Pathogens; Volume 10; Issue 12; Pages: 1547 Pathogens Pathogens, MDPI, 2021, 10 (12), pp.1547. ⟨10.3390/pathogens10121547⟩ Pathogens, Vol 10, Iss 1547, p 1547 (2021) |
| ISSN: | 2076-0817 |
| DOI: | 10.3390/pathogens10121547 |
| Popis: | In South Africa, the prevalence of cattle handler exposure to Brucella on cattle farms is unknown and risk factors and cattle symptoms associated with infected cattle herds are unavailable. To address this gap, a case-control study of cattle herds was conducted in Gauteng province and farm workers and veterinary officials were tested for exposure to Brucella. Seroprevalence amongst farm workers exposed to case herds ranged from 4.0% (BrucellaCapt®) to 16.7% (IgG ELISA®), compared to those exposed to control herds, where seroprevalence ranged from 1.9% (BrucellaCapt®) to 5.7% (IgG ELISA®). Seroprevalence amongst veterinary officials was significantly greater compared to farm workers exposed to case herds for the outcome RBT+ IgM- IgG+ (OR = 11.1, 95% CI: 2.5–49.9, p = 0.002) and RBT- IgM- IgG+ (OR = 6.3, 95% CI: 2.3–17.3, p < 0.001). Risk factors associated with being an infected herd were: being a government-sponsored farm vs. private farm (OR 4.0; 95% CI: 1.4–11.3; p = 0.009), beef vs. dairy herd (OR 7.9; 95% CI: 1.4–44.9; p = 0.020), open vs. closed herd (OR 3.3; 95% CI: 1.1–10.4; p = 0.038) and the presence of antelope on the farm (OR 29.4; 95% CI: 4.0–218.2; p = 0.001). Abortions (OR = 5.1; 95% CI: 2.0–13.3; p < 0.001), weak calves in the herd (OR = 8.0; 95% CI: 2.6–24.4; p < 0.001), reduction in number of calves born (OR = 9.0; 95% CI: 2.1–43.6; p < 0.001), reduction in conception rate (OR = 3.9; 95% CI: 0.8–18.3; p = 0.046), hygromas in cattle (p = 0.011) and farmers reporting brucellosis-like symptoms in their farm workers or in him/herself (OR = 3.4; 95% CI: 1.3–8.7; p = 0.006) were more likely to be associated with Brucella infected herds than control herds. This evidence can be used in strategic planning to protect both human and herd health. |
| Databáze: | OpenAIRE |
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