Determination of pentraxin 3 levels in diagnosis of appendicitis in children
| Autor: | Murat Çakmak, Mustafa Durmaz, Hüseyin Dindar, Ufuk Ateş, İmge B. Ergüder, Fatih Gunay, Ergun Ergün, Meltem Bingol-Kologlu, Kutay Bahadır, Aydin Yagmurlu, Gülnur Göllü |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Future studies Neutrophils Gastroenterology Internal medicine Leukocytes Humans Medicine Right lower quadrant pain Lymphocyte Count Child Pentraxin-3 Inflammation Perforated Appendicitis Receiver operating characteristic biology business.industry C-reactive protein Area under the curve Appendicitis medicine.disease Abdominal Pain Serum Amyloid P-Component C-Reactive Protein ROC Curve Pediatrics Perinatology and Child Health biology.protein Female business Biomarkers |
| Zdroj: | Pediatrics International. 62:624-628 |
| ISSN: | 1442-200X 1328-8067 |
| Popis: | BACKGROUND The aim of this study is to determine whether pentraxin 3 (PTX3) levels can be used in the diagnosis of appendicitis in children. METHODS Fifteen children under 18 years old, who gave blood samples for reasons other than inflammatory conditions, and 40 children who were proved to have appendicitis (non-perforated or perforated) between August 2017 and January 2018, were enrolled in the study. Patients were classified into subgroups: group 1 (healthy children without any sign of inflammation, n = 15), group 2 (non-perforated appendicitis, n = 25), and group 3 (perforated appendicitis, n = 15). RESULTS The median PTX3 value was 1.01 ng/mL (minimum value: 0.82, maximum: 1.28) in the control group. The median PTX3 values prior to surgery were 20.68 ng/mL (minimum: 1.02, maximum: 28.471) and 1.46 (minimum: 1.05, maximum: 23.421) ng/mL for non-perforated appendicitis and perforated appendicitis respectively. The PTX3 levels were significantly higher in groups 2 and 3 than in group 1 (P |
| Databáze: | OpenAIRE |
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