Who Were Hospitalized Deceased Patients from COVID-19 During the First Year of Pandemic? Retrospective Analysis of 1104 Deceased Patients in South of France

Autor: Sylvie Arlotto, Kevin Legueult, Alice Blin, Sebastien Cortaredona, Audrey Giraud-Gatineau, Laurent Bailly, Marie-Thérèse Jimeno, Léa Delorme, Philippe Brouqui, Jean-Christophe Lagier, Matthieu Million, Jean Dellamonica, Philippe Colson, Michel Carles, Didier Raoult, Christian Pradier, Stéphanie Gentile
Přispěvatelé: Aix-Marseille Université - École de médecine (AMU SMPM MED), Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU)-Aix Marseille Université (AMU), Hôpital l'Archet, Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Centre Hospitalier Universitaire de Nice (CHU Nice), Service de l'Information Médicale [Marseille], Hôpital de la Timone [CHU - APHM] (TIMONE), Hôpital Nord [CHU - APHM], Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), CHU Nice [Cimiez], Hôpital Cimiez [Nice] (CHU), Centre d'Information et de Soin de l'Immuno-déficience Humaine Nice, CISIH Nice
Rok vydání: 2022
Předmět:
Zdroj: Journal of Epidemiology and Global Health
Journal of Epidemiology and Global Health, 2022, ⟨10.1007/s44197-022-00039-3⟩
ISSN: 2210-6014
2210-6006
Popis: Introduction Following the first year of the COVID-19 pandemic, a complete analysis of the characteristics of the deceased hospitalized patients was performed, to identify factors related to premature mortality and to compare patient profiles according to the epidemic periods. Methods Retrospective analysis of 1104 deceased patients in two University Hospitals in South-eastern France, between March 1, 2020 and March 12, 2021 from Hospital’s electronic medical records was performed. Results Mean age was 80 years (± 11.1) and 10% of the deceased were younger than 65 years with specific comorbidities, e.g., genetic conditions, metastatic cancer, or massive obesity. Among the three clusters identified, two clusters (75% of deceased patients) include very elderly patients with numerous comorbidities, and differ by their proportion of dependent institutionalized patients. The third cluster is made up of younger patients with fewer but severe comorbidities. Deceased patients’ profiles varied according to the epidemic periods: during the first period (March–June 2020), more patients were institutionalized. The second period (September–December2020) coincided with a higher mortality rate. Conclusions This study confirmed that most patients hospitalized and dying from COVID-19 were frail, i.e., elderly and/or highly comorbid and that the small proportion of young patients had severe comorbidities.
Databáze: OpenAIRE
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