Regulatory Mechanisms of Mitochondrial Autophagy: Lessons From Yeast
| Autor: | Aleksei Innokentev, Tomotake Kanki, Kentaro Furukawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Mini Review
CK2 Far complex Plant Science Oxidative phosphorylation Biology Mitochondrion yeast lcsh:Plant culture 03 medical and health sciences 0302 clinical medicine Atg32 Mitophagy lcsh:SB1-1110 030304 developmental biology 0303 health sciences Mechanism (biology) Ppg1 Yeast Cell biology Mitochondrial autophagy mitochondria mitophagy Selective degradation Molecular mechanism 030217 neurology & neurosurgery |
| Zdroj: | Frontiers in Plant Science, Vol 10 (2019) Frontiers in Plant Science |
| DOI: | 10.3389/fpls.2019.01479/full |
| Popis: | Mitochondria produce the majority of ATP required by cells via oxidative phosphorylation. Therefore, regulation of mitochondrial quality and quantity is important for maintaining cellular activities. Mitophagy, the selective degradation of mitochondria, is thought to contribute to control of mitochondrial quality and quantity. In recent years, the molecular mechanism of mitophagy has been extensively studied in yeast and mammalian cells. In particular, identification of the mitophagy receptor Atg32 has contributed to substantial progress in understanding of mitophagy in yeast. This review summarizes the molecular mechanism of mitophagy in yeast and compares it to the mechanism of mitophagy in mammals. We also discuss the current understanding of mitophagy in plants. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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