Organophosphate pesticide exposure among farm women and children: Status of micronutrients, acetylcholinesterase activity, and oxidative stress
Autor: | Padmaja R. Jonnalagadda, Venkaiah Kodali, Babban Jee, Srujana Medithi, Yogeswar Dayal Kasa |
---|---|
Rok vydání: | 2020 |
Předmět: |
Adult
Male Diazinon Adolescent Health Toxicology and Mutagenesis India Nutritional Status 010501 environmental sciences Biology Toxicology 01 natural sciences Pesticide toxicity 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Occupational Exposure Humans Phosalone Micronutrients Child 0105 earth and related environmental sciences General Environmental Science Farmers Pesticide residue Organophosphate Public Health Environmental and Occupational Health Pesticide Residues Middle Aged Micronutrient 030210 environmental & occupational health people.cause_of_death Organophosphates Oxidative Stress chemistry Chlorpyrifos Acetylcholinesterase Malathion Female people |
Zdroj: | Archives of environmentaloccupational health. 77(2) |
ISSN: | 2154-4700 |
Popis: | Nutritional status plays a major role in determining the possible adverse health outcomes due to pesticide toxicity. The objective of the present study was to assess the organophosphorus pesticide residue levels among farm women (FW) (24-45years) and farm children (FC) (9-12 and 13-15years) belonging to the Rangareddy district (Telangana, India) along with their micronutrient status, inhibition of acetylcholinesterase activity, and oxidative stress levels. Residues of Chlorpyrifos, Diazinon, Malathion, Monocrotophos and Phosalone were found in the serum samples of FW and FC along with significantly low levels of vitamins and minerals. Inhibition of AChE activity was observed in FW and FC and altered oxidative stress parameters among FW. Correlation studies have found significant associations between the pesticide residues, micronutrients and antioxidant enzymes. The study suggests an association between pesticide exposure coupled with micronutrient deficiency, induced AChE inhibition, and oxidative stress. |
Databáze: | OpenAIRE |
Externí odkaz: |