Seven Cases of Radiation-Induced Cutaneous Squamous Cell Carcinoma
| Autor: | Yoshinori Suenaga, Osamu Yamamoto, Kazunari Sugita |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Neoplasms Radiation-Induced Skin Neoplasms Cutaneous squamous cell carcinoma medicine.medical_treatment Radiation induced Skin Diseases Occupational Exposure Humans Medicine Aged Radiotherapy integumentary system business.industry Public Health Environmental and Occupational Health General Medicine Middle Aged medicine.disease Dermatology Radiation exposure Radiation therapy Carcinoma Squamous Cell Female Chronic radiodermatitis Occupational exposure Differential diagnosis Skin cancer business |
| Zdroj: | Journal of UOEH. 22:259-267 |
| ISSN: | 2187-2864 0387-821X |
| DOI: | 10.7888/juoeh.22.259 |
| Popis: | We report 7 cases of radiation-induced skin cancer. The diagnosis was based on the history of radiotherapy for benign skin diseases (5 cases) and of occupational exposures to medical doctors (2 cases). All cases were squamous cell carcinomas which arose from chronic radiodermatitis. The estimated latent period of these tumors ranged from 6 to 64 years, with an average of 29.9 years. After surgical treatments of the lesions, no local recurrences were observed in all cases. Benign skin diseases had sometimes been treated with low-energy radiation before the 1960s. Considering the estimated latent period, the peak time point of developing risk of radiation-induced skin cancer by such treatment has been already passed, however, the danger of it should not be ignored in future. In association with multiplicity of radiation usage, occupational exposure of radiation may develop the risk of occurrence of skin cancer in future. Therefore, we should recognize that radiation-induced skin cancer is not in the past. In the cases of chronic skin diseases showing warty keratotic growth, erosion and ulcer, we should include chronic radio-dermatitis in the differential diagnosis. It is necessary to recall all patients about the history of radiotherapy or radiation exposure. Rapid histopathological examination is mandatory because of the suspicion of radiation-induced skin cancer. |
| Databáze: | OpenAIRE |
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