Comparison of FDG PET/MRI and FDG PET/CT in Pediatric Oncology in Terms of Anatomic Correlation of FDG-positive Lesions
| Autor: | Arzu Okur, Cesur Samanci, Uğuray Aydos, Lebriz Uslu-Beşli, Ceyda Karadeniz, Faruk Güçlü Pınarlı, Lütfiye Özlem Atay Kapucu, Ümit Özgür Akdemir, Zühre Kaya, Nese Ilgin Karabacak |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Adolescent Standardized uptake value Medical Oncology Multimodal Imaging Pediatrics Correlation 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Neoplasms Positron Emission Tomography Computed Tomography Image Interpretation Computer-Assisted Pediatric oncology Effective diffusion coefficient Medicine Humans Child Fluorodeoxyglucose medicine.diagnostic_test business.industry Infant Magnetic resonance imaging Hematology Magnetic Resonance Imaging carbohydrates (lipids) Oncology 030220 oncology & carcinogenesis Child Preschool Positron-Emission Tomography Pediatrics Perinatology and Child Health Fdg pet ct Female Tomography Radiopharmaceuticals business Nuclear medicine 030215 immunology medicine.drug |
| Zdroj: | Journal of pediatric hematology/oncology. 41(7) |
| ISSN: | 1536-3678 |
| Popis: | The aims of our study were to compare F-18 fluorodeoxyglucose (FDG) positron-emission tomography/magnetic resonance imaging (PET/MRI) and PET/computed tomography (CT) in pediatric oncology patients in terms of anatomic correlation of FDG-positive lesions, and also to compare diffusion-weighted imaging (DWI) with PET to assess the correlation between apparent diffusion coefficient (ADC) values and standardized uptake value (SUV). Sequential PET/CT and PET/MRI images and/or whole-body DWI and ADC mapping in 34 pediatric patients were retrospectively analyzed. FDG-positive lesions were visually scored for CT, T1-weighted, T2-weighted, and DWI images separately in terms of anatomic correlation of FDG-avid lesions. Correlation analysis was performed for SUV parameters and ADC values. Among 47 FDG-positive lesions identified concurrently on PET/CT and PET/MRI, 37 were positive on CT and 46 were positive on at least one MRI sequence (P=0.012). Among 32 FDG-positive lesions for which DWI were available, 31 could be clearly depicted on DWI, resulting in significant difference compared with CT alone in the detection of FDG-positive lesions. No correlation was found between ADC and SUV. FDG PET/MRI exhibits better performance than PET/CT in terms of anatomic correlation of FDG-avid lesions. Therefore, PET/MRI may be more advantageous than PET/CT, not only due to reduced ionizing radiation dose but also for a better depiction of FDG-avid lesions in pediatric PET imaging. |
| Databáze: | OpenAIRE |
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