Risk factors for recurrent spontaneous pneumothorax: A population level analysis

Autor: Douglas J. Mathisen, David C. Chang, Michael Lanuti, Brooks V. Udelsman, Ashok Muniappan
Rok vydání: 2022
Předmět:
Zdroj: The American Journal of Surgery. 223:404-409
ISSN: 0002-9610
DOI: 10.1016/j.amjsurg.2021.05.017
Popis: We sought to determine the rate and risk factors of recurrent spontaneous pneumothorax in a diverse population.Cohort study using the California Public Discharge Data file (1995-2010). We identified patients with first-time spontaneous pneumothorax. The primary outcome was recurrent pneumothorax. Associations with clinical, patient, and hospital characteristics were assessed using Cox regression analysis.Among 14,609 patients with a first-time episode of spontaneous pneumothorax, 26.2% developed a recurrence. Risk factors included age35 (Hazard Ratio [HR] 1.24 95%-Confidence Interval [CI] 1.14-1.36), Asian race (HR 1.24, CI 1.13-1.37), and tube thoracostomy (HR 1.2, CI 1.15-1.31). Mechancial pleurodesis (HR 0.37 CI 0.31-0.45) was superior to chemical pleurodesis (HR 0.71 CI 0.58-0.86) in reducing recurrence risk.The risk of recurrent pneumothorax is greatest in patients age35, Asians, and those requiring a tube thoracostomy. The risks of operative intervention should be balanced against patient risk for recurrence.
Databáze: OpenAIRE