Weight reduction is not a major reason for improvement in rheumatoid arthritis from lacto-vegetarian, vegan or Mediterranean diets

Autor: Lars Sköldstam, Lars Brudin, Gunnar Johansson, Linda Hagfors
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Male
Medicin och hälsovetenskap
Mediterranean diet
Arthritis
Medicine (miscellaneous)
Logistic regression
Diet
Mediterranean
Medical and Health Sciences
law.invention
Arthritis
Rheumatoid
Randomized controlled trial
Weight loss
law
Surveys and Questionnaires
Activities of Daily Living
Prospective Studies
lcsh:RC620-627
Pain Measurement
diet intervention
Cross-Over Studies
Nutrition and Dietetics
Diet
Vegetarian
Vegan Diet
Middle Aged
lcsh:Nutritional diseases. Deficiency diseases
Treatment Outcome
Rheumatoid arthritis
Female
medicine.symptom
lcsh:Nutrition. Foods and food supply
medicine.medical_specialty
Rheumatoid Arthritis
lcsh:TX341-641
Clinical nutrition
body weight
Internal medicine
Weight Loss
medicine
Humans
Acute-Phase Reaction
Analysis of Variance
therapy
business.industry
Research
vegan diet
medicine.disease
lacto-vegetarian diet
Physical therapy
business
Zdroj: Nutrition Journal, Vol 4, Iss 1, p 15 (2005)
Nutrition Journal
ISSN: 1475-2891
Popis: Objectives Several investigators have reported that clinical improvements of patients with rheumatoid arthritis (RA), from participating in therapeutic diet intervention studies, have been accompanied by loss of body weight. This has raised the question whether weight reduction per se can improve RA. In order to test this hypothesis, three previously conducted diet intervention studies, comprising 95 patients with RA, were pooled. Together with Age, Gender, and Disease Duration, change during the test period in body weight, characterised dichotomously as reduction or no reduction (dichoΔBody Weight), as well as Diet (dichotomously as ordinary diet or test diet), were the independent variables. Dependent variables were the difference (Δ) from baseline to conclusion of the study in five different disease outcome measures. ΔESR and ΔPain Score were both characterised numerically and dichotomously (improvement or no improvement). ΔAcute Phase Response, ΔPhysical Function, and ΔTender Joint Count were characterised dichotomously only. Multiple logistic regression was used to analyse associations between the independent and the disease outcome variables. Results Statistically significant correlations were found between Diet and three disease outcome variables i.e. ΔAcute-Phase Response, ΔPain Score, and ΔPhysical Function. Δ Body Weight was univariately only correlated to ΔAcute-Phase Response but not significant when diet was taken into account. Conclusion Body weight reduction did not significantly contribute to the improvement in rheumatoid arthritis when eating lacto-vegetarian, vegan or Mediterranean diets.
Databáze: OpenAIRE
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