Outbreak of Type 1 Wild Poliovirus Infection in Adults, Namibia, 2006
| Autor: | Desta Tiruneh, Alfred Mawela, Claire Chauvin, Jeannette Rainey, Tina Allies, Rosalina de Wee, Noah Mataruse, Nicksy Gumede, Norbert Foster, Abdoulie Jack, Cara C. Burns, Nasir Yusuf, Custodia Mandlhate, Mark A. Pallansch, Margaret A. Watkins, Robert Bossarte, Deo Nshimirimana |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Adolescent Flaccid paralysis medicine.disease_cause Virus Disease Outbreaks Young Adult Immunity Paralysis Humans Immunology and Allergy Medicine Sex Distribution Child Poliovirus type business.industry Poliovirus Age Factors Infant Newborn Infant Outbreak Middle Aged medicine.disease Namibia Virology Poliomyelitis Infectious Diseases Case-Control Studies Child Preschool Female Topography Medical medicine.symptom business |
| Zdroj: | The Journal of Infectious Diseases. 210:S353-S360 |
| ISSN: | 1537-6613 0022-1899 |
| Popis: | A paralytic poliomyelitis outbreak occurred in Namibia in 2006, almost exclusively among adults. Nineteen cases were virologically confirmed as due to wild poliovirus type 1 (WPV1), and 26 were classified as polio compatible. Eleven deaths occurred among confirmed and compatible cases (24%). Of the confirmed cases, 97% were aged 15-45 years, 89% were male, and 71% lived in settlement areas in Windhoek. The virus was genetically related to a virus detected in 2005 in Angola, which had been imported earlier from India. The outbreak is likely due to immunity gaps among adults who were inadequately vaccinated during childhood. This outbreak underscores the ongoing risks posed by poliovirus importations, the importance of maintaining strong acute flaccid paralysis surveillance even in adults, and the need to maintain high population immunity to avoid polio outbreaks in the preeradication period and outbreaks due to vaccine-derived polioviruses in the posteradication era. |
| Databáze: | OpenAIRE |
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