Regional distribution of perchloric acid soluble proteins during the development of rat brain
| Autor: | Ragnar Lund Karlsen, Elisabeth Wedege |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Male
Cerebellum Aging Nerve Tissue Proteins Retina Midbrain chemistry.chemical_compound Developmental Neuroscience Mesencephalon Cortex (anatomy) medicine Animals Perchloric acid Cerebral Cortex Medulla Oblongata Perchlorates biology Brain Rats Inbred Strains DNA Molecular biology Staining Rats medicine.anatomical_structure Histone nervous system Neurology chemistry Biochemistry Liver Solubility Medulla oblongata biology.protein Electrophoresis Polyacrylamide Gel Female sense organs |
| Zdroj: | Developmental neuroscience. 5(2-3) |
| ISSN: | 0378-5866 |
| Popis: | The regional contents of perchloric acid (PCA)-soluble proteins were determined during the development of rat brain. The soluble proteins in cortex, mesencephalon and medulla oblongata decreased gradually to adult age, whereas the levels in cerebellum increased significantly 12 days after birth followed by a decline to adult age. The developmental changes in the soluble proteins in retina, which showed the highest content of these proteins, were different from that of the other regions. Changes in the staining intensities of the main protein bands following SDS-gel electrophoresis were observed during the development of all regions. The patterns of the soluble proteins from retina and cerebellum were less complex than those of the other brain regions and liver and resembled that of the chromosomal high-mobility group proteins and H 1 histones. |
| Databáze: | OpenAIRE |
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