Primary cutaneous lymphoma in Argentina: a report of a nationwide study of 416 patients
| Autor: | Ana C. Acosta, Evelyn Andrea Zambrano Franco, María Inés Fontana, Marina Narbaitz, Mariana Arias, Roberto Chuit, Natallia Torres, Mirta Orentrajch, Silvia Vanzulli, Maria L. Garcia Pazos, Alejandra Abeldaño, Andrea B. Cervini, Paula A Enz, Matias Maskin, Marta A. Villareal |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Lymphoma B-Cell Skin Neoplasms Adolescent CD30 Argentina Lymphoproliferative disorders CBCL Dermatology Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences Mycosis Fungoides 0302 clinical medicine medicine Humans Sezary Syndrome Young adult Child Lymphoma Follicular Aged Aged 80 and over Mycosis fungoides business.industry Incidence Incidence (epidemiology) Infant Newborn Infant Cancer Middle Aged medicine.disease Lymphoma Lymphoma Extranodal NK-T-Cell Child Preschool 030220 oncology & carcinogenesis Female business |
| Zdroj: | International Journal of Dermatology. 58:449-455 |
| ISSN: | 0011-9059 |
| DOI: | 10.1111/ijd.14262 |
| Popis: | Background The aim of this study was to determine the relative frequency of primary cutaneous lymphoma (PCL) in Argentina according to the new World Health Organization (WHO)-European Organization for the Research and Treatment of Cancer (EORTC) classification system. Methods A total of 416 patients from 21 dermatology services were included during a 5-year period (2010-2015); these patients were classified using WHO-EORTC criteria. Results There were 231 (55.2%) males and 185 (44.8%) females; the male-to-female ratio was 1.35. The median age of the patients was 57 years (range, 0-90 years). Most patients were Caucasian (79%), and only 16% of patients were registered as Amerindian. Most patients (387/416, 93%) had cutaneous T-cell lymphoma (CTCL); 28 patients (6.7%) were diagnosed with cutaneous B-cell lymphoma (CBCL). The most frequent CTCL subtypes, in decreasing order of prevalence, were mycosis fungoides (MF), including its variants (75.7%); CD30+ primary cutaneous lymphoproliferative disorders (7.2%); and Sezary syndrome (SS) (3.1%). Cutaneous follicle center lymphoma was the most common CBCL subtype (2.9%). In the subset of patients ≤20 years of age, the most common condition was MF (57%), followed by extranodal NK-T nasal-type lymphoma (14%). Conclusions This study revealed relatively higher rates of MF and lower rates of CBCL in Argentinean patients that have been reported in American and European countries. |
| Databáze: | OpenAIRE |
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