Evaluation of copy number variations reveals novel candidate genes in autism spectrum disorder-associated pathways

Autor:	Ren-Hua Chung, Harry H. Wright, Laura D. Nations, Michael L. Cuccaro, Anthony J. Griswold, Ramkumar Menon, Patrice L. Whitehead, Ruth K. Abramson, Daria Salyakina, James M. Jaworski, Michael A. Schmidt, Holly N. Cukier, Ioanna Konidari, Eden R. Martin, Jonathan L. Haines, Margaret A. Pericak-Vance, Deqiong Ma, Scott M. Williams, John R. Gilbert
Rok vydání:	2012
Předmět:	Male Candidate gene Adolescent DNA Copy Number Variations Population Single-nucleotide polymorphism Biology Polymorphism Single Nucleotide Young Adult Receptors GABA mental disorders Genetics Humans Genetic Predisposition to Disease Copy-number variation Child education Molecular Biology Genetics (clinical) education.field_of_study Association Studies Articles General Medicine FMR1 Child Development Disorders Pervasive Case-Control Studies Child Preschool GABAergic Female Candidate Disease Gene Algorithms GRID1
Zdroj:	Human Molecular Genetics. 21:3513-3523
ISSN:	1460-2083 0964-6906
Popis:	Autism spectrum disorders (ASDs) are highly heritable, yet relatively few associated genetic loci have been replicated. Copy number variations (CNVs) have been implicated in autism; however, the majority of loci contribute to
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1a9e5eb5b14a69590aa2d72f982080 https://doi.org/10.1093/hmg/dds164 Zobrazit plný text záznamu