Regional chromosomal localization of the human gene for galactose-1-phosphate uridyltransferase

Autor: N. C. Sun, Ernest H. Y. Chu, C. R. Y. Sun
Rok vydání: 1977
Předmět:
Zdroj: Human genetics. 37(3)
ISSN: 0340-6717
Popis: Summary. In the progeny of somatic cell hybrids formed by fusion of human lymphocytes and Chinese hamster mutant cells, a single human chromosome A2 was selectively retained when grown in appropriate medium. Spontaneous breakage of this chromosome in different hybrid subclones led to the assignment of the gene for galactose-l-phosphate uridyltransferase to the centromeric region of this chromosome (2qll-2q14). This gene is shown to be syntenic to the previously mapped genes for acid phosphatase 1 and malate dehydrogenase 1.
Databáze: OpenAIRE