Antibacterial effect of Blumea balsamifera (L.) DC. essential oil against Staphylococcus aureus
| Autor: | Lu Wang, Jiamei Liao, Li Long, Hui Yang, Junchao Peng, Yue Gao, Yalin Cai |
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| Rok vydání: | 2021 |
| Předmět: |
Staphylococcus aureus
Microbial Sensitivity Tests Asteraceae medicine.disease_cause Biochemistry Microbiology law.invention Cell membrane 03 medical and health sciences law Oils Volatile Genetics medicine Molecular Biology Essential oil 030304 developmental biology chemistry.chemical_classification 0303 health sciences biology 030306 microbiology Chemistry Pathogenic bacteria General Medicine biology.organism_classification Anti-Bacterial Agents medicine.anatomical_structure Enzyme Proteome Nucleic acid Blumea balsamifera Drugs Chinese Herbal |
| Zdroj: | Archives of Microbiology. 203:3981-3988 |
| ISSN: | 1432-072X 0302-8933 |
| DOI: | 10.1007/s00203-021-02384-6 |
| Popis: | Staphylococcus aureus (S. aureus) is a common pathogenic bacteria in clinical environment, which can cause various diseases. Blumea balsamifera (L.) DC. as a traditional Chinese herb, its essential oil shows excellent bacteriostatic effect against S. aureus. To study the antibacterial effect of B. balsamifera (L.) DC. essential oil (BBO) against S. aureus, this study evaluated the effect of BBO on the permeability and integrity of cell membranes and on the total protein and nucleic acid content in S. aureus. Furthermore, proteomics was used to study the effect of BBO on the proteome of S. aureus. The results showed that BBO can destroy the permeability of the cell membrane, and inhibit the synthesis of bacterial nucleic acid and protein. Proteomics shows that BBO affects disorder of amino acid metabolism and affects the activity of various enzymes and the transport of substances. Taken together, these results indicated a substantial antibacterial effect of BBO on S. aureus. |
| Databáze: | OpenAIRE |
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