Predicting the outcome of respiratory disease in wheezing infants using tidal flow-volume loop shape
| Autor: | C.J. Cela, L. García Marcos, P. Cornes, Esteban N. Keklikian, Jose A. Castro-Rodriguez, M. Sanchez Solis |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Respiratory rate Sedation Immunology 03 medical and health sciences 0302 clinical medicine Internal medicine Tidal Volume medicine Humans Immunology and Allergy Lung function Respiratory Sounds Asthma business.industry Respiratory disease Infant General Medicine medicine.disease Asthma predictive index Respiratory Function Tests Loop (topology) 030228 respiratory system Child Preschool Cardiology Female medicine.symptom business 030215 immunology |
| Zdroj: | Allergologia et Immunopathologia. 48:355-359 |
| ISSN: | 0301-0546 |
| Popis: | Introduction and objectives Wheezing (RW) infants with a positive asthma predictive index (API+) have a lower lung function as measured by forced expiratory techniques. Tidal flow-volume loops (TFVL) are easy to perform in infants, and sedation is not necessary. Materials and methods A total of 216 wheezing infants were successfully measured, and 183 of them were followed for over a year. TFVL loops were classified into one of three categories depending of their geometric shape (symmetric, convex, and concave). Respiratory rate (Rr), presence of API+, and the number of exacerbations during the following year were also recorded. Results Children with concave loops had more exacerbations in the following year (OR = 6.8 [IC95% 3.33;13.91]). Infants API + were also significantly more related to concave loops (OR = 10.02 [IC 95% 4.53; 22.15]). Rr was higher in infants with concave loops (44+/−15.5 vs. 36.6 +/−12.6; p Conclusion Infants with a concave TFVL have a higher probability of experiencing exacerbations in the following year, and are at a higher risk of suffering asthma. |
| Databáze: | OpenAIRE |
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