Full wave 3D inverse scattering transmission ultrasound tomography in the presence of high contrast

Autor: David T. Borup, John C. Klock, Nasser Pirshafiey, Bilal H. Malik, James W. Wiskin
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Materials science
Tissue Fixation
Breast imaging
Mathematics and computing
media_common.quotation_subject
lcsh:Medicine
Contrast Media
Paediatric research
01 natural sciences
Article
Bone and Bones
030218 nuclear medicine & medical imaging
03 medical and health sciences
High impedance
0302 clinical medicine
Medical research
Imaging
Three-Dimensional
Formaldehyde
0103 physical sciences
Image Processing
Computer-Assisted
Contrast (vision)
Humans
Knee
lcsh:Science
010301 acoustics
Tomography
Whole body imaging
media_common
Ultrasonography
Artifact (error)
Multidisciplinary
lcsh:R
Resolution (electron density)
Paraxial approximation
Computational science
Health care
Translational research
Magnetic Resonance Imaging
Ultrasound Tomography
Ultrasonic Waves
Inverse scattering problem
Cancellous Bone
Three-dimensional imaging
lcsh:Q
Medical imaging
Algorithms
Biomedical engineering
Zdroj: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
ISSN: 2045-2322
Popis: We present here a quantitative ultrasound tomographic method yielding a sub-mm resolution, quantitative 3D representation of tissue characteristics in the presence of high contrast media. This result is a generalization of previous work where high impedance contrast was not present and may provide a clinically and laboratory relevant, relatively inexpensive, high resolution imaging method for imaging in the presence of bone. This allows tumor, muscle, tendon, ligament or cartilage disease monitoring for therapy and general laboratory or clinical settings. The method has proven useful in breast imaging and is generalized here to high-resolution quantitative imaging in the presence of bone. The laboratory data are acquired in ~ 12 min and the reconstruction in ~ 24 min—approximately 200 times faster than previously reported simulations in the literature. Such fast reconstructions with real data require careful calibration, adequate data redundancy from a 2D array of 2048 elements and a paraxial approximation. The imaging results show that tissue surrounding the high impedance region is artifact free and has correct speed of sound at sub-mm resolution.
Databáze: OpenAIRE
Externí odkaz: