The synthesis and characterization of some novel 5-chloro-2-(substituted alkoxy)-N-phenylbenzamide derivatives
| Autor: | Ioana M. C. Ienaşcu, Iuliana Popescu, Alina D. Zamfir, Mirabela A. Padure, Alfa Xenia Lupea |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Chemistry
Hydrazine Biological activity General Chemistry Ethyl ester lcsh:Chemistry chemistry.chemical_compound lcsh:QD1-999 Methyl Ketone Amide Alkoxy group Organic chemistry hydrazones Fourier transform infrared spectroscopy o-substituted salicylanilides hydrazides 5-chloro-2-(substituted alkoxy)-n-phenylbenzamide derivatives ethyl esters |
| Zdroj: | Journal of the Serbian Chemical Society, Vol 74, Iss 8-9, Pp 847-855 (2009) Journal of the Serbian Chemical Society, Vol 74, Iss 8-9, Pp 846-855 (2009) |
| ISSN: | 1820-7421 0352-5139 |
| Popis: | To obtain biologically active compounds, the synthesis of some new derivatives with an o-hydroxybenzamide structure was performed. The ethyl esters 4-6 were obtained by the reaction of 5-chloro-2-hydroxy-N-phenylbenzamide and chloro-substituted acid ethyl esters 1-3 in ethyl methyl ketone. The obtained ethyl esters were condensed with hydrazine yielding the hydrazides 7-8. The hydrazones 11-14 were obtained by the reaction of the hydrazides and the chloro-substituted benzaldehydes 9-10. All the newly synthesized compounds were characterized by FTIR, 1H-NMR, 13C-NMR, MS and elemental analyses. |
| Databáze: | OpenAIRE |
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