N-Iodosuccinimide — An effective reagent for regioselective heterocyclization of o-cyclohex-2′-enylanilines for the synthesis of hexahydrocarbazoles

Autor:	U. K. Kundu, Nirmal K. Jana, Krishna C. Majumdar, B. Roy, U. Das
Rok vydání:	2005
Předmět:	chemistry.chemical_compound Chemistry Reagent Organic Chemistry Organic chemistry Regioselectivity General Medicine General Chemistry Acetonitrile N-iodosuccinimide Medicinal chemistry Catalysis
Zdroj:	Canadian Journal of Chemistry. 83:63-67
ISSN:	1480-3291 0008-4042
DOI:	10.1139/v04-162
Popis:	A number of carbazoles are synthesized in good yields by the N-iodosuccinimide mediated heterocyclization of o-cyclohex-2′-enylanilines in acetonitrile at –10 °C for 45 min followed by heating with palladium–charcoal (10%) in benzene (80 °C) for 18–20 h.Key words: N-iodosuccinimide, hexahydrocarbazole, heterocyclization, carbazole, Claisen rearrangement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e604a57b564be0e47bb03cd6fedf0f https://doi.org/10.1139/v04-162 Zobrazit plný text záznamu Plný text ve formátu PDF